Demographical and biological characteristics of patients with SARS-CoV-2– and SARS-CoV-2+
| Patients with COVID-19−
Median (IQR: Q1–Q3) | Patients with COVID-19+
Median (IQR: Q1–Q3) | P value | |
| Age (years) | 80 (59.6–87.6) | 76.8 (56–86.3) | 0.64 |
| Gender (%male) | 50 | 50 | 1 |
| BMI (kg/m²) | 28.5 (24.9–34.1) | 24.5 (22.4–26.2) | 0.067 |
| Oxygen (RA/OT/MV) | 10/3/3 | 7/5/4 | 0.55 |
| Hemoglobin (g/L) | 116 (100.5–123.5) | 116.5 (102–129.3) | 0.816 |
| RBCs (T/L) | 3.9 (3.2–4.2) | 3.9 (3.3–4.5) | 0.59 |
| MCV (fL) | 92.3 (89.7–96.6) | 90.2 (88.4–93.5) | 0.112 |
| PC (109 /L) | 245.5 (120–321.8) | 205 (165.3–286.8) | 0.926 |
| WBC (109 /L) | 9.7 (6.5–11.6) | 6.3 (4.4–8.8) | 0.088 |
| Lymphocyte (109 /L) | 1.1 (0.7–1.8) | 1 (0.8–1.5) | 0.759 |
| Iron (µmol/L) | 9.5 (7.5–11) | 6.5 (5–13.5) | 0.191 |
| Transferrin (g/L) | 1.9 (1.1–2.3) | 1.6 (1.2–2) | 0.446 |
| Transferrin saturation (%) | 23.6 (16–31.5) | 21.4 (14.2–27.1) | 0.545 |
| Ferritin (µg/L) | 450 (237–761) | 600 (338–1495) | 0.346 |
| sTfR (mg/L) | 3.5 (2.9–4.7) | 3.2 (2.6–4.8) | 0.574 |
| CRP (mg/L) | 24.3 (5.1–75.2) | 38.8 (4.7–149) | 0.417 |
| Hepcidin (nmol/L) | 14.2 (5.95–18.98) | 44.1 (16.55–70.48) | 0.003 |
| ERFE (ng/mL) | 0.89 (0.19–3.82) | 0.16 (0.01–0.73) | 0.035 |
| GDF-15 (pg/mL) | 4713 (2082–7774) | 2003 (1355–2447) | 0.015 |
BMI, body mass index; CRP, C reactive protein; ERFE, erythroferrone; GDF-15, growth differentiation factors 15; MCV, mean corpuscular volume; MV, mechanical ventilation; OT, oxygen therapy; PC, platelet count; RA, room air; RBC, red blood count; sTfR, soluble transferrin receptor; WBC, white blood cell.