Table 1

Patients’ characteristics

CharacteristicsNSTI, n=80
Age (years)61 (52—68)
Sex, male52 (65)
BMI (kg/m2)26 (24—31)
Comorbidities
 Cardiovascular disease35 (44)
 Chronic kidney disease5 (6)
 COPD6 (8)
 Diabetes21 (26)
 Immune deficiency2 (3)
 Liver cirrhosis1 (1)
 Malignancy7 (9)
 Peripheral vascular disease11 (14)
 Rheumatoid disease4 (5)
Polyicrobial versus monomicrobial
 Monomicrobial infections30 (37)
 Polymicrobial infections42 (53)
 Negative findings8 (10)
Biochemistry
 Leukocyte count (109/L)15 (10–22)
 C reactive protein (mg/L)221 (148–324)
 Creatinine (µmol/L)109 (78–181)
 Lactate (mmol/L)2.3 (1.3–3.3)
Other
 SOFA score*8 (6–10)
 SAPS II†44 (35–51)
 LRINEC‡8 (7–10)
 Septic shock on admission§39 (49)
 Amputation within 7 days13 (16)
 RRT within 7 days12 (15)
 Mortality, day 9012 (15)
  • Continuous data are presented as medians (IQR) and categorical data as absolute numbers (percentage, %).

  • *SOFA score, day 1; data were missing for three (4%) patients.

  • †Data were missing for three (4%) patients.

  • ‡Data were missing for eight (10%) patients.

  • §Septic shock defined as lactate>2 mmol/L and use of vasopressor or inotrope.

  • BMI, Body Mass Index; COPD, chronic obstructive pulmonary disease; LRINEC, Laboratory Risk Indicator for Necrotizing Fasciitis Score; NSTI, necrotizing soft-tissue infection; RRT, renal-replacement therapy; SAPS II, Simplified Acute Physiology Score II; SOFA, Sequential Organ Failure Assessment.