Risk factor (sample size) | Unadjusted | Adjusted† | ||||

OR | 95% CI | P value | OR | 95% CI | P value | |

Bromhexine (n=48) vs standard treatment (n=52) | 1.09 | 0.18 to 6.67 | 0.93 | 0.24 | 0.007 to 8.03 | 0.43 |

Obese‡ (n=47) vs not obese (n=53) | 1.13 | 0.18 to 6.96 | 0.89 | 0.48 | 0.02 to 12.71 | 0.66 |

Renal disease (n=5) vs no renal disease (n=95) | 26.72 | 3.02 to 236.50 | 0.003 | 24.98 | 2.40 to 259.71 | 0.007 |

Smoker (n=13) vs non-smoker (n=87) | 0.69 | 0.03 to 14.96 | 0.81 | 1.02 | 0.06 to 18.67 | 0.99 |

*ORs were calculated from logistic regression models that used Firth’s penalized maximum likelihood estimation.

†Each OR is adjusted for the remaining variables that are found in the table.

‡Defined as a Body Mass Index of ≥30 kg/m

^{2}.