Risk factor (sample size) | Unadjusted | Adjusted† | ||||

OR | 95% CI | P value | OR | 95% CI | P value | |

Bromhexine (n=48) vs standard treatment (n=52) | 0.92 | 0.15 to 5.66 | 0.93 | 4.15 | 0.13 to 138.25 | 0.43 |

Obese‡ (n=47) vs not obese (n=53) | 0.88 | 0.14 to 5.43 | 0.89 | 2.11 | 0.08 to 56.39 | 0.66 |

Renal disease (n=5) vs no renal disease (n=95) | 0.04 | 0.004 to 0.33 | 0.003 | 0.04 | 0.004 to 0.42 | 0.007 |

Smoker (n=13) vs non-smoker (n=87) | 1.46 | 0.07 to 31.67 | 0.81 | 0.99 | 0.05 to 18.14 | 0.99 |

*ORs were calculated from logistic regression models that used Firth’s penalized maximum likelihood estimation.

†Each OR is adjusted for the remaining variables that are found in the table.

‡Defined as a Body Mass Index of ≥30 kg/m

^{2}.