Table 2

The association between baseline goal-striving stress (GSS) and rapid kidney function decline (incidence rate ratio (IRR) 95% CI), JHS 2000–2013 (n=2630)

VariableStatistic
IRR (95% CI)
Model 1
 Low GSSReference
 Moderate GSS1.15 (0.81 to 1.63) p=0.4374
 High GSS1.73 (1.120 to 2.48) p=0.0031*
 Continuous GSS0.032 (0.006 to 0.059) p=0.0152*
Model 2
 Low GSSReference
 Moderate GSS1.13 (0.80 to 1.61) p=0.4758
 High GSS1.63 (1.13 to 2.34) p=0.0085*
 Continuous GSS0.028 (−0.001 to 0.053) p=0.0396*
Model 3
 Low GSSReference
 Moderate GSS1.18 (0.83 to 1.67) p=0.3669
 High GSS1.61 (1.12 to 2.32) p=0.0101*
 Continuous GSS0.026 (−0.001 to 0.052) p=0.0557
Model 4
 Low GSSReference
 Moderate GSS1.17 (0.83 to 1.67) p=0.3707
 High GSS1.60 (1.11 to 2.14) p=0.0119
 Continuous GSS0.025 (−0.002 to 0.051) p=0.0665
Model 5
 Low GSSReference
 Moderate GSS1.16 (0.82 to 1.65) p=0.4072
 High GSS1.58 (1.09 to 2.30) p=0.0153
  • Model 1: adjusted for age, sex, and education.

  • Model 2: model 1+smoking status, alcohol use status, and physical activity status.

  • Model 3: model 2+body mass index (BMI), hypertension, diabetes, and cardiovascular disease.

  • Model 4: model 3+discrimination.

  • Model 5: model 4+baseline cortisol.

  • *Significant p values.

  • JHS, Jackson Heart Study.