Abstract B21 Table 2

Study findings

Pre-TAVR echocardiogram (n=50)Post-TAVR first echocardiogram (mean: 32 days) (n=47)Post-TAVR follow-up echocardiogram (mean: 336 days) (n=22)Change from post-TAVR first to follow-up echocardiogram
Mean ± SDMean ± SD95% CIp-valueMean ± SD95% CIp-valueMean [95% CI]p-value
LV mass, g 259.1 ± 108 243.4 ± 94.0 [-22.8,66.8] 0.32 236.7 ± 83.3 [-36.0,141.0] 0.22 6.7 [-12.3, 65.9] 0.16
LV mass index, g/m² 126.1 ± 49.6 118.2 ± 41.1 [-13.8,26.9] 0.51 118.2 ± 34.6 [-20.4,60.1] 0.3 0 [-8.18, 154.2] 0.073
LV ejection fraction,% 57.5 ± 14 56.7 ± 13.8 [-3.38, 3.92] 0.88 56.6 ± 16.2 [-6.50, 6.04] 0.94 0.1 [-9.52, 8.99] 0.95
AV mean gradient, mmHg 36.1 ± 18.2 9.0 ± 4.8 [21.7, 33.2] *1.78 x10-12 12.2 ± 6.5 [13.5, 28.0] *8.91 x10-6 -3.2 [-3.41, 2.26] 0.67
AV peak gradient, mmHg 61.7 ± 29.9 17.5 ± 9.3 [36.3, 55.1] *1.3 x10-12 20.9 ± 10.3 [21.0, 47.2] *2.96 x10-5 -3.4 [-3.88, 5.17] 0.77
AV peak velocity, cm/s 357.8 ± 96.3 199.9 ± 60.9 [141.9, 211.5] *3.26 x10-13 223.4 ± 48.6 [95.8, 177.7] *9.29 x10-7 -23.5 [-33.6, 19.8] 0.59
AV VTI, cm 88.8 ± 29.7 34.6 ± 7.7 [14.4, 68.0] *0.011 51.5 ± 15.0 [12.0, 55.0] *0.006 -16.9 [-41.6, 35.9] 0.52
AV area, cm² 0.77 ± 0.24 1.83 ± 0.52 [-1.18, -0.75] *1.93 x10-9 1.64 ± 0.45 [-1.03, -0.49] *2.20 x10-5 0.19 [-0.18, 0.55] 0.28
AV area index, cm²/m² 0.4 ± 0.13 0.93 ± 0.3 [-0.61, -0.39] *8.63 x10-10 0.82 ± 0.25 [-0.52, -0.24] *3.62 x10-5 0.11 [-0.07, 0.35] 0.17
Aortic root diameter, cm 3.14 ± 0.49 3.17 ± 0.43 [-0.20, 0.23] 0.87 2.89 ± 0.47 [-0.033, 0.57] 0.076 0.28 [-0.18, 0.51] 0.31
LVOT diameter, cm 2.14 ± 0.55 2.08 ± 0.19 [-0.088, 0.066] 0.77 2.1 ± 0.26 [-0.29, 0.62] 0.46 -0.02 [-0.21, 0.11] 0.51
LVOT peak velocity, cm/s 91.9 ± 26.3 96.8 ± 25 [-11.8, 4.62] 0.38 112.9 ± 33.2 [-35.4, -1.52] *0.034 -16.1 [-38.3, 2.51] 0.081
LVOT peak gradient, mmHg 4.88 ± 7.91 4.99 ± 2.52 [-3.25, 2.91] 0.88 6.0 ± 3.11 [-4.33, 0.33] 0.085 -1.01 /
LVOT mean velocity, cm/s 76 ± 49.7 73.0 ± 19.9 [-119.1, 141.8] 0.74 68.9 ± 26.4 [-24.9, -1.60] *0.036 4.1 /
LVOT mean gradient, mmHg 3.24 ± 6.11 2.72 ± 1.47 [-5.04, 5.09] 0.98 2.97 ± 1.50 [-1.46, 0.058] 0.06 -0.25 /
LVOT VTI, cm 20.9 ± 6.0 19.2 ± 5.51 [-5.25, 5.51] 0.95 24.6 ± 6.56 [-5.28, 4.38] 0.84 -5.4 [-12.8, 12.6] 0.94
LVOT stroke volume, ml 78.1 ± 29.7 71.4 ± 18.2 [-294.2, 296.7] 0.97 86.1 ± 47.6 [-98.7, 108.4] 0.66 -14.7 /
LVOT stroke volume index, ml/m² 39.6 ± 14.4 37.3 ± 9.9 [-156.1, 157.1] 0.98 43.3 ± 20.4 [-45.1, 49.2] 0.68 -6 /
LVOT cardiac output, ml/min 5852 ± 2443 5456 ± 1771 [-1829, 1250] 0.25 6123 ± 2422 [-1088, 1338] 0.42 -667 /
LVOT cardiac index, ml/min·m² 2904 ± 1015 2821 ± 948 [-9519, 6487] 0.25 3065 ± 1068 [-431, 730] 0.19 -244 /
DVI with LVOT VTI 0.25 ± 0.069 0.64 ± 0.21 [-0.57, -0.09] *0.018 0.51 ± 0.16 [-0.38, -0.11] *0.0031 0.13 [-0.77, 0.82] 0.74
  • *statistically significant, p-value <0.05

  • AV: aortic valve, CI: confidence interval, DVI: doppler velocity index, LV: left ventricle, LVOT: left ventricular outflow tract, SD: standard deviation, TAVR: transcatheter aortic valve replacement, VTI: velocity time integral,/: no statistical data available