Table 3

Definitions of acute and long-term response

Acute pulmonary vasoreactivity for patients with idiopathic, heritable or drug-induced PAH.Reduction of mPAP >10 mm Hg to reach an absolute value of mPAP <40 mm Hg.
Increased or unchanged cardiac output.
Long-term response to CCBs.New York Heart Association functional class I/II.
With sustained hemodynamic improvement (same or better than achieved in the acute test) after at least 1 year on CCBs only.
  • CCBs, calcium channel blockers; mPAP, mean pulmonary arterial pressure; PAH, pulmonary arterial hypertension.