Table 3

Methylation analysis of MIR200C/MIR141 cluster in CRC patients and reference group

MIR200C/MIR141 clusterCRC patientsReference group
Tumor tissue
n=51 (%)*†
Adjacent normal tissue
n=51 (%)*
Peripheral blood
n=40 (%)†
Peripheral blood
n=40 (%)
Methylated and unmethylated alleles48 (94)49 (96)8 (20)5 (12.5)
Only methylated alleles2 (4)2 (4)32 (80)35 (87.5)
Only unmethylated alleles1 (2)0 (0)00
  • *Comparisons between colorectal tissues of CRC patient were not significant (p>0.05).

  • †Comparisons between colorectal tissues versus peripheral blood of CRC patients or versus reference group were significant (p<0.0001).

  • CRC, colorectal cancer.