Table 3

Univariate analysis of differences among patients with sepsis or septic shock admitted to the department of internal medicine

CharacteristicsSepsis
(74 patients)
Septic shock
(9 patients)
P value
Demographics
 Gender (male)38 (51.4%)3 (33.3%)0.483
 Age (years)65.7±20.079.8±15.40.016
Comorbidities
 Charlson Comorbidity Index3.1±2.15.0±2.40.016
 COPD10 (13.5%)1 (11.1%)1.000
 Cerebrovascular accident8 (10.8%)2 (22.2%)0.296
 Diabetes mellitus13 (17.6%)2 (22.2%)0.663
 Malignancy (haematological or solid organ)6 (8.1%)1 (11.1%)0.567
Admission data
 Duration of symptoms before admission (days)2.8±2.92.0±2.10.224
 Leucocytes (109/L)16.3±5.712.7±6.50.128
 C reactive protein (mg/dL) on admission14.9±8.712.9±8.40.662
 Temperature (°C)38.7±0.737.9±1.30.093
 SAPS II Score on admission37.9±14.561.1±13.5<0.001*
 SOFA Score on admission4.0±1.98.4±2.2<0.001*
 Acute kidney injury11 (14.9%)8 (88.9%)<0.001
 LOS (days)10.9±9.013.2±16.40.866
Type of infection
 Pneumonia23 (31.1%)3 (33.3%)1.000
 Urinary tract infection31 (41.9%)5 (55.6%)
 Abdominal infection13 (17.6%)0 (0.0%)
 Other 7 (9.5%)1 (11.1%)
 Bacteraemia11 (14.9%)4 (44.4%)0.052
 Microbiological confirmed30 (40.5%)4 (44.4%)1.000
 Gram-positive3 (4.1%)2 (22.2%)
 Gram-negative27 (36.5%)2 (22.2%)
 Coagulation disorders on admission6 (8.1%)4 (44.4%)0.010
 INR1.2±0.21.3±0.30.115
 PTT (s)34.4±7.940.3±10.00.079
 Platelets (109/L)250.0±110.6191.0±116.20.110
 Fibrinogen (g/L)650.1±183.7489.5±139.50.297
 D-dimers (ng/mL)2781.6±2684.13767.5±3131.70.392
  • *Factors were not included in the multivariate analysis.

  • †Comparison between patients with pneumonia against all other causes.

  • ‡Skin and soft-tissue infections and endocarditis.

  • SAPS II, Simplified Acute Physiology Score II.