Table 2

Body composition and anthropometry

Brain tumor survivors (BTS)NHANES III
Reference population
Radiation exposure to the HPA n=60No radiation exposure to the HPA
n=82
n=1878
Median (IQRs)P value RE vs no RE*Median (IQRs)†P value for comparisons to BTS
Body mass index19.6 (17.6, 21.1)20.4 (19.3,21.9)0.5121.0 (20.9, 21.3)0.36
Body mass index z-score0.43 (−0.24, 0.8)*0.79 (0.55, 1.1)0.014
Waist circumference (cm)76 (71, 83)†79 (74, 82)†0.9574.2 (73.8, 74.6)<0.001
Body composition (% of total body mass)
 Body fat38.1 (31.2, 39.8)†33.6 (30.6, 35.9)†0.1524.2 (23.6, 24.8) <0.001
 Lean mass58.6 (57.2, 65.4)*†63.0 (60.6, 65.8)†0.01573.0 (72.4, 73.6) <0.001
 Bone mineral content2.9 (2.8, 3.1)†3.1 (2.9, 3.4)†0.293.6 (3.6, 3.6) <0.001
 Body fat/lean mass ratio0.64 (0.48, 0. 69)†0.52 (0.47, 0. 60)†0.160.34 (0.32, 0.35) <0.001
 Truncal fat15.7 (12.9, 17.7)†13.6 (11.2, 15.8)†0.238.8 (8.6, 9.1) <0.001
 Appendicular fat mass19.0 (16.2, 19.8)†17.2 (16.0, 19.2)†0.182.7 (2.6, 2.8) <0.001
 Appendicular lean mass24.4 (23.3, 27.1)†26.9 (24.4, 28.0)†0.4332.9 (32.6, 33.3) <0.001
Abdominal fat (% of total body mass)
 Subcutaneous abdominal fat7.74 (5.21, 8.44)6.95 (5.21, 7.64)0.20
 Visceral fat2.07 (1.79, 2.17)*1.57 (1.26, 1.82)0.002
  • *Significantly different from the brain tumor survivors who did not have radiation exposure to the HPA.

  • †Significantly different from the reference NHANES group.

  • HPA, hypothalamus-pituitary-adrenal axis; RE, radiation exposure.