Clinical characteristics
| Criteria | Hypothalamic radiation | |
| Exposed | Not Exposed | |
| Number of subjects | 60 | 82 |
| Males (%) | 60.0 | 52.4 |
| Median (IQRs) | ||
| Age at study evaluation (years) | 14.1 (12.6, 15.4) | 11.9 (9.9, 13.0) |
| Survival time (years) | 4.5 (3.5, 5.5) | 6.3 (4.3, 7.4) |
| Age at diagnosis (years) | 7.2 (5.7, 9.0)* | 4.9 (3.6, 5.6) |
| Diagnosis (% of total) | ||
| Medulloblastoma | 40.0† | 2.4 |
| Germinoma | 13.3† | 0.0 |
| Pilocytic astrocytoma | 11.7† | 50.0 |
| Ependymoma | 13.3† | 2.4 |
| Atypical teratoid rhabdoid tumor | 5.0 | 1.2 |
| Other | 16.7† | 43.9 |
| Radiation plus chemotherapy therapy (%) | 78.3† | 0.0 |
| Race (%) | ||
| White | 55 | 53.7 |
| Black | 15 | 11.0 |
| Hispanic | 30 | 26.8 |
| Other | 0 | 8.5 |
*Significantly different from group not exposed to radiation treatment. P=0.001; two-tailed t-test.
†Significantly different from group not exposed to radiation treatment. P<0.01; Χ2 test.