Comparison of metabolic features in subjects exposed to radiation and treated with growth hormone with subjects not exposed to radiation nor treated with growth hormone
| Hypothalamic radiation | P value | ||
| Exposed (plus growth hormone treatment) | Not Exposed (no growth hormone treatment) | ||
| Mean (SD) | |||
| Glucose (mg/dL) | 86 (8) | 78 (9) | >0.001 |
| HOMA-IR* (%) | 1.05 (0.42, 1.8) | 0.69 (0.52, 1.0) | 0.03 |
| C-peptide* (ng/mL) | 1.4 (1.1, 1.7) | 1.9 (1.4, 2.6) | 0.26 |
| IGF-1* (ng/mL) | 156 (121, 170) | 194 (159, 289) | 0.63 |
| Adiponectin* (μg/mL) | 13.2 (10.1, 17.3) | 14.1 (6.4, 18.4) | 0.67 |
| Leptin* (ng/mL) | 10.5 (5.7, 21.7) | 10.0 (4.4, 20.3) | 0.67 |
| Triglycerides (mg/dL) | 105 (57) | 87 (48) | 0.19 |
| HDL cholesterol (mg/dL) | 54 (16) | 54 (14) | 1.0 |
| Systolic blood pressure (mm Hg) | 116 (12) | 114 (13) | 0.50 |
| Diastolic blood pressure (mm Hg) | 66 (8) | 65 (8) | 0.61 |
*Medians (IQRs).
HDL, high-density lipoprotein; HOMA-IR, homeostasis model assessment of insulin resistance; IGF-1, insulin-like growth factor-1.