Table 4

Prevalence of metabolic risk factors and metabolic syndrome

Metabolic parameter (% of subgroup)Hypothalamic radiationP value
ExposedNot Exposed
Metabolic syndrome15.0*4.90.03
Metabolic syndrome treated for growth hormone deficiency3.8NA
Metabolic syndrome not treated for growth hormone deficiency11.2NA
Prevalence of metabolic risk factors (%)
Waist circumference>gender-specific27.432.50.51
Elevated fasting glucose0.01.20.29
Triglyceride>150 mg/dL25.0*8.60.02
High-density lipoprotein cholesterol<40 mg/dL25.014.60.12
Systolic blood pressure>130 mm Hg9.715.70.29
History of growth hormone deficiency (%)40.7*3.7 <0.001
Treated for growth hormone deficiency (%)37.3*2.5 <0.001
  • *Significantly different from group not exposed to radiation therapy; Χ2 test.

  • NA, not applicable for comparisons since subjects were not treated for growth hormone deficiency.