Test (n) | Overall | Degree of initial abnormality | p-value | ||
---|---|---|---|---|---|

1–2 X ULN (n=5874) | >2–4 X ULN (n=256) | >4 X ULN (n=25) | |||

Bili (1679) | 13.7% | 13.7% | 13.2% | 22.2% | 0.753 |

AST (3017) | 10.7% | 10.9% | 6.8% | 20.0% | 0.217 |

ALT (838) | 16.8% | 16.9% | 9.1% | - | 0.701 |

ALP (621) | 12.7% | 13.0% | 6.7% | 33.3% | 0.148 |

p-value | <0.001 | <0.001 | 0.410 | 0.854 |