Table 2

Serum PCSK9 and cholesterol concentrations and non-cholesterol sterol ratios to cholesterol after consumption of butter and CPTRO

VariablesButter n=37CPTRO n=37p Value
PCSK9, ng/mL214.2 (191.2 to 237.2)229.3 (197.1 to 229.3)0.248
Cholesterol, mmol/L5.30 (4.87 to 5.73)4.92 (4.50 to 5.33)<0.001
Markers of cholesterol synthesis
 Squalene*14.9 (10.5 to 19.2)13.7 (10.4 to 17.1)0.792
 Cholestenol*17.0 (12.1 to 22.0)16.5 (9.8 to 23.2)0.850
 Desmosterol*95.2 (79.7 to 110.7)89.0 (78.2 to 99.8)0.792
 Lathosterol*122.6 (85.3 to 159.8)111.0 (72.8 to 149.3)0.645
Markers of cholesterol absorption efficiency
 Cholestanol*138.3 (128.0 to 148.6)138.1 (126.4 to 149.7)0.541
 Campesterol*199.7 (150.3 to 249.1)277.0 (224.0 to 330.0)<0.001
 Sitosterol*97.7 (86.3 to 109.2)113.1 (104.0 to 122.2)<0.001
 Avenasterol*33.0 (27.7 to 38.2)35.0 (28.9 to 41.0)0.734
Marker of cholesterol metabolism
 Lathosterol/cholestanol, µg/ µg0.76 (0.36 to 1.16)0.80 (0.61 to 1.00)0.934
  • Values shown are median and 95% CI of the median except mean and 95% CI of the mean for total cholesterol.

  • *100 x μmol/mmol of cholesterol.

  • CPTRO, cold-pressed turnip rapeseed oil; PCSK9, proprotein conversin subtilisin/kexin 9.