Article Text

PDF
Clinical features of patients with male breast cancer in Shanxi province of China from 2007 to 2016
  1. Weigang Wang1,
  2. Xiaoqin Xu1,
  3. Baoguo Tian1,
  4. Yan Wang1,
  5. Lili Du1,
  6. Ting Sun1,
  7. Yanchun Shi1,
  8. Xianwen Zhao1,
  9. Yali Jia2,
  10. Yanfeng Xi3,
  11. Jiexian Jing1
  1. 1Department of Etiology and Tumor Marker Laboratory, Shanxi Cancer Hospital, Shanxi, China
  2. 2Department of Preventive Health Care, Shanxi Cancer Hospital, Shanxi, China
  3. 3Department of Pathology, Shanxi Cancer Hospital, Shanxi, China
  1. Correspondence to Professor Jiexian Jing, Department of Etiology and Tumor Marker Laboratory, Shanxi Cancer Hospital, Shanxi, China; 2912972872{at}qq.com

Abstract

This study aims to understand the clinical features, treatment, and prognosis of patients with male breast cancer (MBC) in Shanxi province of China from 2007 to 2016. Data for 77 patients with MBC were collected for analysis. Immunohistochemistry, pathological results, and other data such as demographic characteristics (age, marital status, smoking history, drinking history, and family history of cancer) as well as clinical data were investigated by retrieving information from the patients’ medical records. A total of 12,404 patients were diagnosed with breast cancer between 2007 and 2016, and 77 were patients with MBC among them. The median diagnosis age of patients with MBC was 62 years (range, 24–84 years). The most common complaint was a painless lump in the breast, accounting for 68.8% of the patients, and the main pathological type in MBC was infiltrating ductal carcinoma (66.2%). In terms of hormone receptors, 80.5% (62/77) of patients with MBC were estrogen receptor positive, 75.3% (58/77) of patients were progesterone receptor positive, and only 6.5% (5/77) of patients were HER2 overexpressing. The multivariant Cox proportional hazards regression analysis showed that M stage is an independent prognostic factor (p=0.018, HR=18.791, 95% CI 1.663 to 212.6). The epidemiological and clinical features of Chinese MBC are similar to that of other countries. As the Chinese public have limited knowledge of MBC, it is necessary to increase awareness among them about it. Further research with a large sample size is required for better understanding of the risks associated with MBC.

  • carcinoma
  • prognosis

Statistics from Altmetric.com

Footnotes

  • Contributors Conception or design of the work: XZ, YJ, YX , JJ. Data collection: WW, XX, BT, YW. Data analysis and interpretation: TS, YS. Drafting the article: WW, LD. Critical revision of the article: JJ. Final approval of the version to be published: JJ.

  • Funding This research was supported by the Natural Science Foundation of Shanxi Province, China (201701D121167).

  • Competing interests None declared.

  • Patient consent Obtained.

  • Ethics approval Ethics Committee of Shanxi Cancer Hospital.

  • Provenance and peer review Not commissioned; externally peer reviewed.

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.