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Original research
Betamethasone induces potent immunosuppression and reduces HIV infection in a PBMC in vitro model

Authors

  • Ross Cromarty Mucosal Immunology Laboratory, CAPRISA, Durban, KwaZulu-Natal, South Africa PubMed articlesGoogle scholar articles
  • Alexander Sigal Africa Health Research Institute (AHRI), Durban, KwaZulu-Natal, South Africa Max-Planck-Institute for Infection Biology, Berlin, Germany PubMed articlesGoogle scholar articles
  • Lenine Julie Liebenberg Mucosal Immunology Laboratory, CAPRISA, Durban, KwaZulu-Natal, South Africa Department of Medical Microbiology, University of KwaZulu-Natal, Durban, KwaZulu-Natal, South Africa PubMed articlesGoogle scholar articles
  • Lyle Robert Mckinnon Mucosal Immunology Laboratory, CAPRISA, Durban, KwaZulu-Natal, South Africa Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Manitoba, Canada PubMed articlesGoogle scholar articles
  • Salim Safurdeen Abdool Karim Mucosal Immunology Laboratory, CAPRISA, Durban, KwaZulu-Natal, South Africa Department of Epidemiology, Columbia University Mailman School of Public Health, New York, New York, USA PubMed articlesGoogle scholar articles
  • Jo-Ann Shelly Passmore Mucosal Immunology Laboratory, CAPRISA, Durban, KwaZulu-Natal, South Africa Institute of Infectious Diseases and Molecular Medicine, University of Cape Town Faculty of Health Sciences, Cape Town, Western Cape, South Africa PubMed articlesGoogle scholar articles
  • Derseree Archary Mucosal Immunology Laboratory, CAPRISA, Durban, KwaZulu-Natal, South Africa Department of Medical Microbiology, University of KwaZulu-Natal, Durban, KwaZulu-Natal, South Africa PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Derseree Archary, Mucosal Immunology Laboratory, CAPRISA, Durban 4013, KwaZulu-Natal, South Africa; desh.archary{at}caprisa.org
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Citation

Cromarty R, Sigal A, Liebenberg LJ, et al
Betamethasone induces potent immunosuppression and reduces HIV infection in a PBMC in vitro model
Journal of Investigative Medicine 2021;69:28-40.

Publication history

  • Accepted August 25, 2020
  • First published October 1, 2020.
Online issue publication 
December 21, 2020

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Copyright information

© American Federation for Medical Research 2021. Re-use permitted under CC BY-NC. No commercial re-use. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, an indication of whether changes were made, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.