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Attention and memory impairments in pediatric patients with cystic fibrosis and inflammatory bowel disease in comparison to healthy controls
  1. Bartosz Piasecki,
  2. Maia Stanisławska-Kubiak,
  3. Wojciech Strzelecki,
  4. Ewa Mojs
  1. Department of Clinical Psychology, Poznan University of Medical Sciences, Poznan, Poland
  1. Correspondence to Dr Bartosz Piasecki, Department of Clinical Psychology, Poznan University of Medical Sciences, Bukowska 70, 60-812 Poznan, Poland; bpiasecki{at}


The main aim of the study was to analyze and compare attention and memory performance in pediatric patients with cystic fibrosis (CF), inflammatory bowel disease (IBD) and in healthy controls. 28 patients with CF, 30 patients with IBD and 30 healthy subjects took part in the study (all in age range of 7–17). All subjects were in intellectual norm. To analyze the functioning of attention, the d2 Test of Attention by Brickenkamp (d2 test) was applied. Memory performance was assessed using the Benton Visual Retention Test (BVRT) and the Trial of 10 words. The CF and IBD groups committed significantly more errors in the d2 test than the healthy controls. The CF group also had significantly higher fluctuation rates and received significantly lower scores in overall concentration performance than the control group. Patients with CF made more mistakes and had fewer correct memory projections in BVRT than the healthy controls. Patients with IBD committed significantly more errors in BVRT than the control group. Patients with CF and IBD also got significantly lower scores in the Trial of 10 words than the control group. Pediatric patients with CF and IBD performed more poorly than the healthy controls on attention and memory tests. More distinct cognitive impairments were observed in the CF group. Further research is needed to find the underlying mechanisms and clinical and/or functional significance of observed cognitive deficits.

  • chronic disease
  • inflammatory bowel diseases
  • neuropsychological tests
  • cognition

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  • Contributors BP and EM conceived the study. BP collected the data and evaluated the data in collaboration with EM, MS-K and WS. BP, MS-K, EM and WS participated in literature search. BP in collaboration with EM performed data analysis, data interpretation, and wrote the manuscript. MS-K and WS contributed substantially to the manuscript revision. All authors read and approved the final manuscript.

  • Competing interests None declared.

  • Patient consent Parental/guardian consent obtained.

  • Ethics approval Approval by the Bioethics Committee at Poznan University of Medical Sciences was obtained and this study has therefore been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments. The participation in the study was preceded by obtaining the consent from the participants and their legal parents (guardians).

  • Provenance and peer review Not commissioned; externally peer reviewed.