Article Text

PDF
52 Effect of external application of spikenard water decoction on the mouse pain model
  1. Peng Xi,
  2. Yan Li,
  3. Xiaojin Ge,
  4. Mingsan Miao
  1. Department of Pharmacology, Henan University of Chinese Medicine, Zhengzhou, China

Abstract

Objectives To investigate the effects of external application of a spikenard water decoction on pain model mice.

Methods We investigated the effects of spikenard water decoction on the pain threshold in mice using the hot plate method. After injection of formaldehyde, the effects of spikenard water decoction on the formalin-induced pain incubation period and biting times were observed.

Results Each dose of spikenard water decoction obviously or significantly improved the pain threshold of pain model mice (p?<?0.01, p < 0.05), significantly prolonged the pain licking incubation period (p<0.01) and obviously or significantly reduced the number of instep licks in 5 min and 10 min (p < 0.01, p < 0.05).

Conclusions External application of spikenard water decoction has a good analgesic effect in the mouse pain model.

Statistics from Altmetric.com

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.