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AMPK/p53 Axis Is Essential for α-Lipoic Acid–Regulated Metastasis in Human and Mouse Colon Cancer Cells

Authors

  • Sunmi Park From the *Laboratory of Metabolic Engineering, Department of Biotechnology, College of Life Sciences and Biotechnology, †Institute of Animal Molecular Biotechnology, and ‡Biomedical Research Center of Guro Hospital, Research Driven Hospital, Korea University, Seoul, South Korea.From the *Laboratory of Metabolic Engineering, Department of Biotechnology, College of Life Sciences and Biotechnology, †Institute of Animal Molecular Biotechnology, and ‡Biomedical Research Center of Guro Hospital, Research Driven Hospital, Korea University, Seoul, South Korea. PubMed articlesGoogle scholar articles
  • Seung Kug Choi From the *Laboratory of Metabolic Engineering, Department of Biotechnology, College of Life Sciences and Biotechnology, †Institute of Animal Molecular Biotechnology, and ‡Biomedical Research Center of Guro Hospital, Research Driven Hospital, Korea University, Seoul, South Korea.From the *Laboratory of Metabolic Engineering, Department of Biotechnology, College of Life Sciences and Biotechnology, †Institute of Animal Molecular Biotechnology, and ‡Biomedical Research Center of Guro Hospital, Research Driven Hospital, Korea University, Seoul, South Korea. PubMed articlesGoogle scholar articles
  • Yura Choi From the *Laboratory of Metabolic Engineering, Department of Biotechnology, College of Life Sciences and Biotechnology, †Institute of Animal Molecular Biotechnology, and ‡Biomedical Research Center of Guro Hospital, Research Driven Hospital, Korea University, Seoul, South Korea.From the *Laboratory of Metabolic Engineering, Department of Biotechnology, College of Life Sciences and Biotechnology, †Institute of Animal Molecular Biotechnology, and ‡Biomedical Research Center of Guro Hospital, Research Driven Hospital, Korea University, Seoul, South Korea. PubMed articlesGoogle scholar articles
  • Hyun-Seuk Moon From the *Laboratory of Metabolic Engineering, Department of Biotechnology, College of Life Sciences and Biotechnology, †Institute of Animal Molecular Biotechnology, and ‡Biomedical Research Center of Guro Hospital, Research Driven Hospital, Korea University, Seoul, South Korea.From the *Laboratory of Metabolic Engineering, Department of Biotechnology, College of Life Sciences and Biotechnology, †Institute of Animal Molecular Biotechnology, and ‡Biomedical Research Center of Guro Hospital, Research Driven Hospital, Korea University, Seoul, South Korea.From the *Laboratory of Metabolic Engineering, Department of Biotechnology, College of Life Sciences and Biotechnology, †Institute of Animal Molecular Biotechnology, and ‡Biomedical Research Center of Guro Hospital, Research Driven Hospital, Korea University, Seoul, South Korea. PubMed articlesGoogle scholar articles
  1. Received July 2, 2015, and in revised form July 22, 2015.
  2. Accepted for publication July 23, 2015.
  3. Reprints: Hyun-Seuk Moon, PhD, Laboratory of Metabolic Engineering, Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul, 136-713, South Korea, E-mail: mhs72{at}korea.ac.kr.
  4. Supported by grants from the Korea University (K1420781), Korea University Guro Hospital (O1500081), and Korea Institute of Oriental Medicine (R1508541).
  5. Conflict of Interest: The authors have declared no conflicts of interest.
  6. S.P. and H.S.M. participated in the study design, performance, and coordination. S.P., S.K.C., Y.C., and H.S.M. contributed to writing the manuscript. H.S.M. conceived the study. All authors read and approved the final article.
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Citation

Park S, Choi SK, Choi Y, et al
AMPK/p53 Axis Is Essential for α-Lipoic Acid–Regulated Metastasis in Human and Mouse Colon Cancer Cells
Journal of Investigative Medicine 2015;63:882-885.

Publication history

  • First published December 15, 2015.
Online issue publication 
December 15, 2015

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