Funding Opportunity Purpose

This FOA will support research on the development of biomarkers for the complications of type 1 diabetes that will use minimally or non-invasive measures of blood vessels and nerves in the eye. A critical obstacle for preventing and treating diabetes complications is the paucity of both biomarkers that can detect changes in blood vessels and nerves before clinical signs develop and surrogate end-points that can measure early responses to an intervention. Given the accessibility of the blood vessels and nerves in the eye for visualization, this FOA invites applications for research using the eye to visualize the development of diabetes complications in the eye and other tissues, such as the kidney, brain, heart and peripheral nerves.

Complete details available at: http://grants.nih.gov/grants/guide/rfa-files/RFA-DK-13-027.html.

Funding Opportunity Purpose

This Funding Opportunity Announcement (FOA) invites one Research Project Cooperative Agreement application (UC4) from the Program Director/Principal Investigator of the TrialNet Data Coordinating Center (TNCC). The mission of TrialNet is to conduct clinical trials aimed at the prevention of type 1 diabetes. This is a one-time FOA to provide funds to the TNCC to conduct 2 new clinical trials or studies, as part of an ongoing consortium of Trial Net investigators, for a maximum of five years, contingent on satisfactory performance. To support the conduct of these trials, TNCC will manage and support a complex network of Clinical Centers, Affiliate Centers, Core Laboratories, Central Pharmacy, and …