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Grants and Contracts

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CONSORTIUM OF LUNG REPAIR AND REGENERATION: BUILDING THE FOUNDATION (U01): RFA-HL-12-006

Also note: Lung Repair and Regeneration Consortium Administrative Coordinating Center (U01): RFA-HL-12-010

Details at: http://grants.nih.gov/grants/guide/rfa-files/RFA-HL-12-010.html

Components of Participating Organizations

National Heart, Lung, and Blood Institute

Application Receipt Date(s): February 10, 2011

The National Heart, Lung, and Blood Institute (NHLBI) invites applicants to participate in the Lung Repair and Regeneration Consortium (LRRC). The goal of the Consortium is to bring together multidisciplinary teams of investigators, cutting edge technologies, innovative strategies, and new ideas to catalyze research on the mechanisms of lung regeneration and repair, and to develop new tools, reagents, and models to elucidate the lung's capacity for regeneration. The Consortium will also contain collaborative research support and skills development components to be administered after the Consortium is assembled through the companion FOA, RFA HL-12-010 "Lung Repair and Regeneration Consortium (U01) Administrative Coordinating Center" in years 27-5. The purpose of this FOA is to develop a highly interactive and synergistic Consortium of investigators who will share ideas, data, and resources to move the field of lung regeneration forward toward development of new therapies for human diseases. This FOA solicits Research Project Cooperative Agreement (U01) applications from institutions/organizations that propose 1) to test innovative hypotheses of mechanisms that control adaptive and maladaptive lung repair/regeneration after injury and include studies to validate these mechanisms are relevant in humans and 2) to develop two or more novel tools (e.g. reagents, models, imaging, and/or data analysis tools) that would accelerate research progress in lung regeneration. LRRC Research Centers will be comprised of multidisciplinary teams that will work collaboratively with other Research Centers in the LRRC to accelerate science in lung repair and regeneration.

Collaboration and interaction between LRRC investigators will be a requirement of the program. The LRRC will be responsible for collaboratively generating, validating, and sharing necessary reagents, models, antibodies, assays, protocols, and technologies …

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