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NIH Common Fund Initiatives Announced

The National Institutes of Health (NIH) announced seven scientific initiatives to be supported through the NIH Common Fund. The programs will distribute $17.8 million in NIH Common Fund support in the 2010 fiscal year and additional funds in future years. The NIH Common Fund, enacted into law by Congress through the 2006 NIH Reform Act, supports trans-NIH programs that require participation by at least two NIH Institutes or Centers (ICs) or would otherwise benefit from strategic planning and coordination.

The seven new scientific programs are:

Science of Behavior Change Program: This initiative will focus on understanding human behavior change across a broad range of health-related behaviors. The program will address strategies to curb unhealthy behaviors such as smoking, drinking, and drug abuse, as well as inactivity and poor diet.

Library of Integrated Network-based Cellular Signatures Program (LINCS): The LINCS program will develop a community resource of scientific information pertaining to biological systems. The initiative will catalogue how components of biological systems - genes, proteins, metabolites and other molecules - function normally and how they become disrupted by genetic and environmental stressors to cause disease. This will be a two-phase initiative.

Protein Capture Reagents Program: This initiative will create a suite of new research tools to isolate proteins in order to study their function under normal conditions and when the cell is stressed or diseased. The program will be accomplished in four phases.

Knockout Mouse Phenotyping Program: This program will explore how specific genes control phenotypes such as metabolism, energy balance, and physical appearance in mice. The initiative will establish a system to characterize the vast collection of knockout mice.

Global Health Program: This program will amplify the capacity for global health research by enhancing education, training and research opportunities in developing countries.

Translational Application of Stem Cells - NIH Induced …

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