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Atorvastatin Affects Interleukin-2 Signaling by Altering the Lipid Raft Enrichment of the Interleukin-2 Receptor β Chain

Authors

  • Jens Goebel From the Divisions of Nephrology and Hypertension (J.G., B.L., A.M.) and Immunobiology (M.W.-K.), Cincinnati Children's Hospital, Cincinnati, OH, and Departments of Pediatrics (J.G., K.F.) and Immunology (T.L.R.), University of Kentucky, Lexington, KY. Supported by National Institutes of Health KO8 grant A1049241, a National Kidney Foundation Young Investigator Award, a University of Kentucky Physician-Scientist award, and by funds from the University of Kentucky Department of Pediatrics, all to J.G. Presented in part at the American Federation for Medical Research-sponsored symposium during Experimental Biology 2005, San Diego, CA, April 2-6, 2005, and in part at the meeting of the International Pediatric Transplantation Society, Rio de Janeiro, Brazil, April 5-9, 2003; the American Transplant Congress, Boston, MA, May 14-19, 2004; and the meeting of the American Society of Nephrology, St. Louis, MO, October 29-November 1, 2004. PubMed articlesGoogle scholar articles
  • Barbara Logan From the Divisions of Nephrology and Hypertension (J.G., B.L., A.M.) and Immunobiology (M.W.-K.), Cincinnati Children's Hospital, Cincinnati, OH, and Departments of Pediatrics (J.G., K.F.) and Immunology (T.L.R.), University of Kentucky, Lexington, KY. Supported by National Institutes of Health KO8 grant A1049241, a National Kidney Foundation Young Investigator Award, a University of Kentucky Physician-Scientist award, and by funds from the University of Kentucky Department of Pediatrics, all to J.G. Presented in part at the American Federation for Medical Research-sponsored symposium during Experimental Biology 2005, San Diego, CA, April 2-6, 2005, and in part at the meeting of the International Pediatric Transplantation Society, Rio de Janeiro, Brazil, April 5-9, 2003; the American Transplant Congress, Boston, MA, May 14-19, 2004; and the meeting of the American Society of Nephrology, St. Louis, MO, October 29-November 1, 2004. PubMed articlesGoogle scholar articles
  • Kathy Forrest From the Divisions of Nephrology and Hypertension (J.G., B.L., A.M.) and Immunobiology (M.W.-K.), Cincinnati Children's Hospital, Cincinnati, OH, and Departments of Pediatrics (J.G., K.F.) and Immunology (T.L.R.), University of Kentucky, Lexington, KY. Supported by National Institutes of Health KO8 grant A1049241, a National Kidney Foundation Young Investigator Award, a University of Kentucky Physician-Scientist award, and by funds from the University of Kentucky Department of Pediatrics, all to J.G. Presented in part at the American Federation for Medical Research-sponsored symposium during Experimental Biology 2005, San Diego, CA, April 2-6, 2005, and in part at the meeting of the International Pediatric Transplantation Society, Rio de Janeiro, Brazil, April 5-9, 2003; the American Transplant Congress, Boston, MA, May 14-19, 2004; and the meeting of the American Society of Nephrology, St. Louis, MO, October 29-November 1, 2004. PubMed articlesGoogle scholar articles
  • Alexandra Mieczkowski From the Divisions of Nephrology and Hypertension (J.G., B.L., A.M.) and Immunobiology (M.W.-K.), Cincinnati Children's Hospital, Cincinnati, OH, and Departments of Pediatrics (J.G., K.F.) and Immunology (T.L.R.), University of Kentucky, Lexington, KY. Supported by National Institutes of Health KO8 grant A1049241, a National Kidney Foundation Young Investigator Award, a University of Kentucky Physician-Scientist award, and by funds from the University of Kentucky Department of Pediatrics, all to J.G. Presented in part at the American Federation for Medical Research-sponsored symposium during Experimental Biology 2005, San Diego, CA, April 2-6, 2005, and in part at the meeting of the International Pediatric Transplantation Society, Rio de Janeiro, Brazil, April 5-9, 2003; the American Transplant Congress, Boston, MA, May 14-19, 2004; and the meeting of the American Society of Nephrology, St. Louis, MO, October 29-November 1, 2004. PubMed articlesGoogle scholar articles
  • Thomas L. Roszman From the Divisions of Nephrology and Hypertension (J.G., B.L., A.M.) and Immunobiology (M.W.-K.), Cincinnati Children's Hospital, Cincinnati, OH, and Departments of Pediatrics (J.G., K.F.) and Immunology (T.L.R.), University of Kentucky, Lexington, KY. Supported by National Institutes of Health KO8 grant A1049241, a National Kidney Foundation Young Investigator Award, a University of Kentucky Physician-Scientist award, and by funds from the University of Kentucky Department of Pediatrics, all to J.G. Presented in part at the American Federation for Medical Research-sponsored symposium during Experimental Biology 2005, San Diego, CA, April 2-6, 2005, and in part at the meeting of the International Pediatric Transplantation Society, Rio de Janeiro, Brazil, April 5-9, 2003; the American Transplant Congress, Boston, MA, May 14-19, 2004; and the meeting of the American Society of Nephrology, St. Louis, MO, October 29-November 1, 2004. PubMed articlesGoogle scholar articles
  • Marsha Wills-Karp From the Divisions of Nephrology and Hypertension (J.G., B.L., A.M.) and Immunobiology (M.W.-K.), Cincinnati Children's Hospital, Cincinnati, OH, and Departments of Pediatrics (J.G., K.F.) and Immunology (T.L.R.), University of Kentucky, Lexington, KY. Supported by National Institutes of Health KO8 grant A1049241, a National Kidney Foundation Young Investigator Award, a University of Kentucky Physician-Scientist award, and by funds from the University of Kentucky Department of Pediatrics, all to J.G. Presented in part at the American Federation for Medical Research-sponsored symposium during Experimental Biology 2005, San Diego, CA, April 2-6, 2005, and in part at the meeting of the International Pediatric Transplantation Society, Rio de Janeiro, Brazil, April 5-9, 2003; the American Transplant Congress, Boston, MA, May 14-19, 2004; and the meeting of the American Society of Nephrology, St. Louis, MO, October 29-November 1, 2004. PubMed articlesGoogle scholar articles
  1. Address correspondence to: Dr. Jens Goebel, Cincinnati Children's Hospital Medical Center, Nephrology and Hypertension, MLC 7022, 3333 Burnet Avenue, Cincinnati, OH 45229-3039; e-mail: Jens.Goebel{at}cchmc.org .
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Citation

Goebel J, Logan B, Forrest K, et al
Atorvastatin Affects Interleukin-2 Signaling by Altering the Lipid Raft Enrichment of the Interleukin-2 Receptor β Chain

Publication history

  • First published December 10, 2015.
Online issue publication 
December 10, 2015

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