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Consequences of Cold Ischemic Injury of Kidneys in Clinical Transplantation
  1. Abdulla K. Salahudeen
  1. From the Department of Medicine, University of Mississippi Medical Center, Jackson, MS.
  2. The related work of the author is supported by National Institutes of Health grant RO-1 DK-56835-01.
  3. Address correspondence to: Dr. Abdulla K. Salahudeen, Department of Medicine, Division of Nephrology, University of Mississippi Medical Center, 2500 N. State Street, Jackson, MS 39216; e-mail: asalahudeen{at}medicine.umsmed.edu.

Abstract

Cold storage allows the effective utilization of organs retrieved for transplantation. However, prolonged cold ischemia contributes to organ damage and increases patients' morbidity and mortality and health care cost. Using recent data from the United Network for Organ Sharing, this paper examines the outcomes of live donor and deceased donor kidney transplants in relation to cold ischemia time.

Key Words
  • cold ischemia time
  • delayed graft function
  • kidney transplant
  • cold storage
  • cold preservation
  • ischemia reperfusion
  • acute renal failure
  • deceased donor kidneys
  • live donor kidneys

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