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Purpose: This Request for Applications (RFA) invites investigators to submit research applications for the George M. O'Brien Kidney Research Centers Program. The emphases for this program are fourfold: 1) to continue to attract new scientific expertise into the study of the basic mechanisms of kidney diseases and disorders; 2) to encourage multidisciplinary research focused on the causes of these diseases; 3) to explore new basic areas that may have clinical research application; and 4) to generate Developmental Research (DR)/Pilot and Feasibility (P&F) studies of 2 years' duration (generally DR/P&F proposals are expected to have limited preliminary data and are reviewed based on the clear development of hypotheses and supporting literature) that are anticipated will lead to …
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