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Purpose: The National Heart, Lung, and Blood Institute (NHLBI) invites applications for support as Comprehensive Sickle Cell Centers that will offer interactive, state-of-the-art programs in basic and translational sickle cell disease research. The primary objective of this Request for Applications (RFA) is to support ten Comprehensive Sickle Cell Centers, and a Statistics and Data Management Center, to carry out research focused on the development of cures or significantly improved treatments for sickle cell disease. This research will include basic research efforts, inter-center collaborative clinical research, and local clinical research, with all three focused on the most promising therapeutic modalities on the horizon today, and each interactive with the others. In addition to their primary focus in research, Comprehensive Sickle Cell Centers will also support career development of young investigators in sickle cell disease …
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