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Purpose: The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) invites cooperative agreement applications for a Coordinating Center to support clinical trials for the primary prevention and treatment of type 2 diabetes in children in the U.S. and Canada. Type 2 diabetes has been traditionally viewed as a disease of adults. Recent epidemiological data reveals an increasing number of cases of type 2 diabetes in the pediatric population, especially among adolescents and in certain minority populations. The rise in type 2 diabetes in children and adolescents is presumed to be a consequence of widespread obesity and decreased physical activity. Clinical trials to develop effective primary prevention strategies for this age group are needed. In addition, the drugs currently available for …
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