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Purpose: This initiative is designed to explore the underlying mechanism(s) of action of hormones and growth factors in the regulation of prostate development, growth, and tumorigenesis. The focus will be on fundamental studies of hormone and growth factor action including the mechanisms of action of nuclear hormones, the role(s) of nuclear accessory proteins and the signal transduction pathways important for nuclear hormone action in prostate. Focus will also be on growth factor action in prostate, including growth factors, binding proteins, …
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