Article Text

Effect of Marital Status on Clinical Outcome of Heart Failure
  1. Taylor Watkins,
  2. Mark Mansi,
  3. Jennifer Thompson, MD,
  4. Ishak Mansi, MD*,
  5. Roy Parish, PharmD‡§
  1. From the *Department of Medicine, Section of General Internal Medicine, San Antonio Military Medical Center; †San Antonio Uniformed Services Health Education Consortium, San Antonio, TX; ‡College of Pharmacy, University of Louisiana Monroe; and §Department of Medicine, Louisiana State University Health Sciences Center, Shreveport, LA.
  1. Received November 30, 2012, and in revised form January 29, 2013.
  2. Accepted for publication February 5, 2013.
  3. Reprints: Roy Parish, PharmD, College of Pharmacy, University of Louisiana Monroe, Shreveport Campus, 1725 Claiborne Ave, Shreveport, LA 71103. E-mail: rparis{at}
  4. Taylor Watkins is a research volunteer in San Antonio Military Medical Center, and an undergraduate student in Trinity University, San Antonio, TX.
  5. Mark Mansi is a Red Cross volunteer in San Antonio Military Medical Center, and a student in Ronald Reagan High School, San Antonio, TX.
  6. The opinions and research contained herein are the private ones of the authors and are not to be considered as official or reflecting the views of the Department of the Army or the Department of Defense.


Background Despite significant advances in pharmacological and nonpharmacological treatment of heart failure (HF), there are more than 1 million HF visits annually to the emergency department. Studies indicate that HF clinical outcome is affected not only by medical interventions but also by social factors such as marital status.

Objectives This study aimed to determine the effect of marital status of HF patients on clinical outcome of HF in a high-risk population.

Methods We reviewed data collected for The Joint Commission in patients admitted with HF at a university hospital serving a high-risk population in Louisiana during the period from June 2003 to September 2004 and followed up until December 2008. Patients were divided into 2 groups, namely, married patients and unmarried patients (including single, divorced, and widowed) based on self-reporting. Primary outcome measures were in-hospital survival and time to readmission. Secondary outcome measures were HF admission rate, average B-type natriuretic peptide, and average troponin-I levels throughout the follow-up period.

Results Of 646 reviewed records, 542, representing 357 patients, were included in the analysis. Of these, 105 patients were married and 245 were unmarried; marital status was missing for 7 patients. Mean (SD) of follow-up period was 2.39 (1.6) years. Marital status was not a significant variable for in-hospital death (hazard ratio, 0.71; 95% confidence interval, 0.35–1.49), or for time to readmission for HF (hazard ratio, 1.16; 95% confidence interval, 0.86-1.56); multiple linear regression analysis identified married status as an independent variable for average B-type natriuretic peptide (parameter estimate = −0.26, P = 0.02) but not for HF admission rate or average troponin-I levels.

Conclusions Married status was not associated with better clinical outcome in HF patients in a high-risk population.

Key Words
  • heart failure
  • hospital admission
  • heart failure exacerbation
  • social factors
  • marital status

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