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Evidence for the Role of Inadequate Vitamin D in Asthma Severity Among Children
  1. Lauren E. Staple, MD*,
  2. Stephen J. Teach, MD, MPH
  1. From the Divisions of *Emergency Medicine and †Allergy and Immunology, Children's National Medical Center, Washington, DC.
  1. Received March 23, 2011, and in revised form June 7, 2011.
  2. Accepted for publication June 9, 2011.
  3. Reprints: Lauren E. Staple, MD, Division of Emergency Medicine, Children's National Medical Center, 111 Michigan Ave, NW, Washington, DC 20010. E-mail: lstaple{at}cnmc.org.

Abstract

Asthma is the most common chronic pediatric medical condition in the United States and accounts for significant morbidity, particularly among minority and disadvantaged populations. Hypovitaminosis D is also highly prevalent throughout the developed world, and many of the risk factors for hypovitaminosis D and asthma are the same. Several recent observational studies have documented a correlation between asthma severity and vitamin D levels; however, there is no strong evidence for causality yet. Until trials of vitamin D supplementation among children with asthma are performed, the role of low levels of vitamin D in causing asthma morbidity will remain unclear.

Key Words
  • asthma
  • vitamin D

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