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GRANTS AND CONTRACTS

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HUMAN MICROBIOME DEMONSTRATION PROJECTS (UH2/UH3): RFA-RM-08-012

Components of Participating Organizations

National Institutes of Health (NIH)

NIH Roadmap Initiatives

National Center for Complementary and Alternative Medicine

National Cancer Institute

National Eye Institute

National Human Genome Research Institute

National Heart, Lung, and Blood Institute

National Institute on Aging

National Institute on Alcohol Abuse and Alcoholism

National Institute of Allergy and Infectious Diseases

National Institute of Arthritis and Musculoskeletal and Skin Diseases

National Institute of Biomedical Imaging and Engineering

National Institute of Child Health and Human Development

National Institute on Deafness and Other Communication Disorders

National Institute of Dental and Craniofacial Research

National Institute of Diabetes and Digestive and Kidney Diseases

National Institute of Environmental Health Sciences

National Institute of General Medical Sciences

National Institute of Mental Health

National Institute of Neurological Disorders and Stroke

National Institute of Nursing Research

National Library of Medicine

Letters of Intent Receipt Date(s): April 22, 2008

Application Receipt Date: May 22, 2008

Earliest Anticipated Start Date(s): April 1, 2009

This funding opportunity announcement (FOA) invites applications for projects that will examine, through molecular approaches, the relationship between changes in the human microbiome and human health and disease. This program is a component of the NIH Roadmap 1.5 Human Microbiome Project (http://nihroadmap.nih.gov/hmp/). This FOA will use the UH2/UH3 cooperative agreement mechanisms to support the demonstration project awards. The program will be funded in 2 phases, as allowed by this mechanism. The initial 1-year pilot phase (UH2) will allow investigators to procure samples and generate data that will be used to support the scale-up phase (UH3), which will be awarded after administrative review to those projects that have the most promise to demonstrate whether or not the human microbiome plays an important role in human health and disease.

The total amount of funds available for these awards is approximately $4 million total costs for the …

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