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71 Q-T DISPERSION ABNORMALITIES IN THE METABOLIC SYNDROME.
  1. P. I. Altieri1,
  2. Y. Figueroa1,
  3. H. Banchs1,
  4. N. Escobales1,
  5. M. J. Crespo1,
  6. J. G. de la Madrid1,
  7. J. C. López1
  1. 1Departments of Medicine and Physiology, University of Puerto Rico, and The Cardiovascular Center of the Caribbean, San Juan, PR.

Abstract

We studied 173 patients with the metabolic syndrome (MS) with an average age of 60 years. Fifty-seven percent were males and 43 percent were females. The mean blood glucose in the MS group was 169 mg%; 97% were diabetic type 2 and 3% were diabetic type 1. The mean body mass was 30 kg/m2. The Q-T interval was measured by standard techniques and corrected by linear correction formula. Q-TC dispersion (QTCD) calculated from the difference between QTCmax and QTC min was 98 ± 4 ms in the MS group and 45 ± 15 ms in the control group (p < .001). A higher incidence of atrial fibrillation was found in the MS group (12% in MS vs 5.9% in controls, p < .001). Ventricular arrhythmias were not observed in the MS group, and the ejection fraction was subnormal (p < .001) when compared with the control group (50 ± 8% vs 62 ± 12%, respectively). These results agree with the observation by Larroude (J Heart Rhythm 2006;3:660-4) regarding Q-T dynamics and variability in paroxysmal atrial fibrillation.

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