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  1. P. I. Altieri1,
  2. Y. Figueroa1,
  3. H. Banchs1,
  4. N. Escobales1,
  5. M. J. Crespo1,
  6. J. G. de la Madrid1,
  7. J. C. López1
  1. 1Departments of Medicine and Physiology, University of Puerto Rico, and The Cardiovascular Center of the Caribbean, San Juan, PR.


We studied 173 patients with the metabolic syndrome (MS), mean age of 60 years. These patients were compared with 600 nondiabetic patients. Fifty-seven percent were males and 43% were females. The mean blood glucose in the MS group was 169 mg%; 97% were diabetic type 2, whereas 3% were diabetic type 1. Mean body mass was 30 kg/m2. The lipid profile of the MS group was normal, including total cholesterol, HDL, LDL, and triglycerides. No significant coronary disease or evidence of strokes was found among the patients studied. The ejection fraction was subnormal when compared with the control group (50 ± 8% vs 62 ± 12%, respectively, p < .001), whereas a higher end-systolic dimension of the left atrium was observed in the MS group (46 ± 10 mm versus 40 ± 8 mm in controls, p < .05). A higher incidence of atrial fibrillation was found in MS patients (12% in MS vs 5.9% in controls, p < .001). These results suggest the presence of a new variant of the MS in the Hispanic population. This variant shows a normal lipid profile, higher incidence atrial fibrillation, absence of ventricular tachycardia, and minimal ischemic heart disease, with no evidence of strokes.

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