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National Institutes of Health (NIH)

National Center for Research Resources (NCRR)

National Institute of General Medical Sciences (NIGMS)

National Heart, Lung, and Blood Institute (NHLBI)

National Institute of Neurological Disorders and Stroke (NINDS)

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The technologies and methods of proteomics remain largely inadequate, particularly with respect to quantitative and real-time measurements. This funding opportunity announcement (FOA) solicits Small Business Innovation Research (SBIR) grant applications from small business concerns (SBCs) that propose the development of broadly applicable research tools that address the core technical challenges in proteomics and glycomics. This includes but is not restricted to robotics, sample preparation and prefractionation, analytic separations, gel and array imaging, quantitation, mass spectrometry, intelligent automated data acquisition, and improved informatics technologies. Technologies that address the unique needs of glycomics and clinical proteomics, described in Section II.I.1 (Research Objectives), are of particular interest. Awards issued under this FOA are contingent on the availability of funds and the submission of a sufficient number of meritorious applications. This FOA will use the SBIR (R43/R44) grant mechanisms for phase I, phase II, and fast-track applications and runs in parallel with an FOA of identical scientific scope, PA-06-129, which solicits applications under the Small Business Technology Transfer (STTR) (R41/R42) grant mechanisms. For this funding opportunity, budgets up to $200,000 total costs per year and time periods up to 2 years for phase I may be requested. Budgets up to $400,000 total costs per year and up to 4 years may be requested for phase II. Only US SBCs are eligible to submit SBIR applications. A SBC is one that, on the date of award for both phase I and phase II funding agreements, …

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