Article Text

  1. Clarita V. Odvina
  1. 1From the Center for Mineral Metabolism, UT Southwestern Medical Center, Dallas, TX
  1. Address correspondence to: Dr. Clarita V. Odvina, Center for Mineral Metabolism, UT Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390-8885; e-mail: clarita.odvina{at}

How Should It Be Treated?


Osteoporosis develops as a result of imbalance between bone resorption and bone formation. A number of effective and safe therapies for osteoporosis are currently available, most of which are inhibitors of bone resorption. However, because osteoporosis is a complex and heterogeneous disease with different pathogenetic factors, defining the role of the different factors in its development is important in formulating a more selective approach to therapy. This review discusses the advantages and disadvantages of the currently available agents used in the management of osteoporosis.

Key Words
  • osteoporosis
  • bone turnover
  • bone quality
  • bone destiny

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