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The US Food and Drug Administration (FDA) recently announced the appointment of William Slikker Jr, PhD, to the position of acting director of the FDA's National Center for Toxicological Research (NCTR), replacing Dan Casciano, PhD, the former NCTR director of more than 6 years. Dr. Casciano will go on to work in the private sector on molecular, cellular, and general toxicology issues, in addition to being an advocate for the move from population-based medicine to personalized medicine. Acting Commissioner of Food and Drugs Andrew von Eschenbach recently noted that Dr. Slikker is distinctively qualified for the position owing to his research and management work with the FDA, most recently as the NCTR's deputy center director for research. The acting commissioner also cited Dr. Slikker as a renowned leader in the field of toxicology, an experienced scientist and educator, and a strong advocate of the NCTR's research program. Dr. Slikker earned a BA degree in biology from the University of California, Santa Barbara, and received his PhD in pharmacology and toxicology from the University of California, Davis. Dr. Slikker currently serves as an adjunct professor at the University of Arkansas in the Department of Pediatrics and Department of Pharmacology and Toxicology. As acting director of the FDA's NCTR, Dr. Slikker will coordinate efforts to identify the biologic effects of potentially toxic chemical, biologic, and physical agents and to develop methods to improve the evaluation of human exposure and vulnerability to such agents. The NCTR is a critical source of information used by the FDA to formulate regulatory decisions and to decrease the risks posed by products regulated by the FDA. As part of advancements associated with the FDA's Critical Path Initiative, the NCTR uses many methods, including genomics, proteomics, and metabonomics-based analytic tools to assess product safety and to detect new …

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