A recent report by Crowther et al (N Engl J Med 2005;352:2477) looked at the efficacy of treatment of women with gestational diabetes to reduce the risk of perinatal complications. They noted a reduction in perinatal complications among those so treated when compared to controls (1 vs 4%). We conducted a retrospective analysis of admissions to the NICU at JCMCH in Johnson City, TN, from 1/1994 to 12/2004 (11 yrs) and compared outcomes among large for gestational age (LGA) infants 6 exposure to mothers with gestational diabetes (A1 or A2) with regard to incidence of congenital anomalies, neonatal complications requiring NICU care, and survival. Table 1 reviews the results:
Our data show a statistically significant increased incidence of CS mode of delivery, percent hypoglycemia requiring IV therapy, and incidence of congenital anomalies while LGA infants with no maternal diabetes exposure required CPR and need for assisted ventilation more often. Tighter control of gestational diabetes is suggested with this retrospective data comparison
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