Background Cyril Toker first described merkel cell carcinoma (MCC), a rare, aggressive, neuroendocrine carcinoma of the skin, in 1972.
Purpose The aim of our study is to review the UCSF experience of treating MCC from 1989 to the present time.
Method A retrospective study using a database of patients treated and followed at UCSF Hospitals.
Results There are 68 patients with MCC presenting on the head and neck (33), extremities (23), torso/trunk (3), vagina (1), parotid gland (1), and NOS (7). To date, 40 of 42 patients are still alive and disease free. The other 2 patients had recurrence as multiple distant metastasis and invasion into adjacent organs. At this time, additional clinical outcome information is being gathered.
Conclusion A significant number of patients had MCC in the head and neck region. The mortality rate of MCC at UCSF is 38.2% at the present time.
I would like to thank the University of British Columbia MD/PhD Program and CIHR for their support.
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