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Purpose: The purpose of this request for applications (RFA) is to support the Pediatric Heart Network (PHN), whose mission it is to improve the health of children and adults with structural congenital heart defects, as well as children with inflammatory heart disease, heart muscle disease, and arrhythmias. The objectives of the PHN are to provide an infrastructure for multicenter collaborative clinical research; to evaluate medical, interventional, and surgical therapies; and to serve as a clinical trial training ground for fellows and junior faculty. The results of Network studies are expected to be widely disseminated and to improve the scientific basis of care for affected individuals.

Applications should propose research pertaining to congenital heart disease in children or adults, inflammatory cardiovascular disease in childhood, cardiac muscle disease in childhood, or arrhythmias. Proposals to study …

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