Purpose Preoperative chemotherapy is the standard of care for patients with locally advanced breast cancer and is used to downsize tumors to allow surgical resection in patients presenting with disease. Patients referred to our university hospital often present with much more advanced disease and have poorer outcomes. By retrospectively reviewing surgical admissions after primary chemotherapy, baseline patient and tumor characteristics can be obtained to generate a small initial database for patient outcomes.
Patients and Methods A search of ICD-9 admission codes in the diagnosis code range 174.0 - MALIG NEO NIPPLE to 175.9 - MAL NEO MALE BREAST NEC at the University of Mississippi Medical Center for the time period of 01/01/02-12/31/03 was performed. Patients were selected from operative and discharge notes if they had received preoperative chemotherapy. Medical charts and pathology and radiology reports were then reviewed. Initial tumor characteristics were compared before and after chemotherapy. Preoperative chemotherapy regimen and duration were evaluated for response in addition to recurrence and survival data.
Results and Conclusions Sixteen patients met the search criteria. Final results and conclusions will be presented at the Southern Regional Meeting of the American Federation for Medical Research.