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Purpose: Substantial data currently exist showing that prostate volume increases with age in middle-aged and older men, after a postpubertal plateau. In addition, the incidence and prevalence of prostate disease increase with age, and are very high in elderly men. The National Institute on Aging (NIA), the National Cancer Institute (NCI), the NIDDK, and the National Institute of Environmental Health Sciences (NIEHS) invite research applications addressing biologic mechanisms related to aging processes that …
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